Metabolism

By engaging three metabolic receptors at once — GLP-1, GIP, and glucagon — retatrutide represents a genuinely new idea in metabolic pharmacology. Here is what triple agonism means, and what the human data shows so far.

Mitochondria do far more than make energy — and their gradual dysfunction sits close to the center of why bodies age. A guide to the biology that has made mitochondria one of the most important targets in longevity research.

A tiny peptide encoded inside the mitochondria may help explain how our cells adapt to exercise and metabolic stress — and it is opening a fascinating window into the biology of aging.